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Ranking the best prenatal vitamins of 2021

Written by John Davis

Last updated: December 8, 2020

If you’re pregnant (or even considering it) and worried about your baby’s health, taking a prenatal vitamin might be something you want to think about to ensure you’re getting all the vitamins and minerals your baby needs to develop properly.

Here are the best prenatal vitamins on the market, ranked.  Afterwards, we’ll look in more detail about how a prenatal vitamin can help you.

Rankings

1. Ritual Essential Prenatal

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Ritual designed Essential Prenatal to be the only prenatal you need.

Ritual’s developed a cult-like following for its simplicity, traceability and ingredients that work best in the body.  It has completely traceable and transparent ingredients — you can see all of the suppliers and their sources on their website — so you know exactly what you’re putting in your body.

The average prenatal contains 20+ ingredients, and most of those are things women already get enough of in their diets.

Plus, not all ingredient forms are created equal: most multis use forms that don’t work well in the body. Ritual’s team of in-house scientists identified the essential nutrients women actually need and put them in a single non-GMO, vegan, gluten-free, patent-pending capsule without any synthetic fillers or colorants.

Then they created a capsule that actually absorbs the vitamins better:


The result?

Vitamins of the future.

They’ve received praise from Wired and The New York Times for their no-nonsense approach and transparency in the “shady” vitamin industry.

One of the better daily habits any women can have.

BodyNutrition.org 2021 women’s prenatal winner.

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2.  Garden of Life Vitamin Code Raw Prenatal

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Garden of Life focuses on deriving its vitamins and minerals from natural sources, and providing them in chelated forms whenever possible.

The ingredients have everything you’ll need in a prenatal vitamin: 80 mg of folate, 2 mg of vitamin B6, and 6 mcg of vitamin B12.

The amount of vitamin B12 may need to be higher, as some scientific sources advocate for raising the recommended B12 intake, as low blood levels of B12 are associated with birth defects.

Garden of Life Vitamin Code lives up to its “raw” namesake with the inclusion of its fruit and vegetable blend as well as its sprout blend.  These include the extracts of dozens of different fruits, vegetables, and sprouted seeds.

Especially if you are drawn to the fruit, vegetable, and sprout concentrates, Garden of Life Vitamin Code Raw Prenatal is a great choice for a prenatal vitamin.

3.  New Chapter Perfect Prenatal Vitamins

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“Perfect” might be a high bar to meet, but New Chapter’s prenatal multivitamin scores pretty well.

It’s got all the essentials in reasonable amounts: 100-300% of your recommended daily intake for most vitamins and minerals, plus extra vitamin B12 (500% of your daily needs) and a small enough amount of calcium so that iron absorption is not inhibited.

The vitamin includes an herbal blend too, with concentrates from brown rice, oats, berries, dandelion, rose hips, and a few other plants.  Additionally, several live culture probiotics are included for digestive health.

A few extracts from sprouted seeds are included too.  These ingredients draw from natural foods that would be a normal part of your diet, so there’s less of a risk of harming yourself or your baby with an untested and unknown herbal extract from an exotic plant.

4.  MegaFood Baby & Me 2

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This best-selling and highly regarded prenatal is based around a philosophy of deriving its primary ingredients from natural instead of synthetic sources.

The vitamins and minerals in MegaFood Baby & Me 2 come from carrots, cabbage, oranges, brown rice, and a species of yeast called S. cerevisiae.

Among the most important vitamins and minerals, MegaFood Baby & Me 2 contains 18 mg of iron, 80 mg of folate, and 4 mg of vitamin B12.

In each of these cases, the amount of these vitamins and minerals is at or above 100% of the recommended daily intake.  Wisely, MegaFood Baby & Me keep the calcium content low, so as not to upset the absorption of iron from the supplement.

The supplement also includes a small fruit and vegetable extract blend, which includes orange, berries, ginger, chamomile, dandelion, and spinach.  It also comes in a vegetarian cellulose capsule, which is good news if you don’t eat animal products.

5.  Thorne Research Basic Prenatal Multivitamin

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From a quick glance at the nutrition label, Thorne Research’s prenatal vitamin formulation looks pretty unremarkable, until you take a closer look.

While most of the standard vitamins and minerals are present in the expected 100-250% of your recommended daily intake, the vitamin B12 content is through the roof at 3,333% of your recommended daily intake.

This aside, metal mineral content is pretty unremarkable: 45 mg of iron (on the high end), 200 mg of calcium (could inhibit iron absorption somewhat), and moderate amounts of other minerals.

Why such a high amount of vitamin B12 specifically?  It is one of the key vitamins for preventing neural tube defects, a very serious birth defect that can occur when intake of these vitamins is low.

6.  Garden of Life Mykind Organics Prenatal Multi

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Want to keep your prenatal vitamin all-natural and vegan-friendly? Garden of Life is the perfect choice. While you do have to sacrifice a bit in terms of dosage and purity, Garden of Life Mykind Organics Prenatal Multi is the way to go if naturally-sourced ingredients that aren’t from animal products are a major priority for you.

7.  Rainbow Light Prenatal One

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As a top-selling traditional multivitamin manufacturer, it only makes sense that Rainbow Light would also sell a prenatal vitamin.  Its formulation is fairly traditional, using a tablet form and delivering mostly-normal amounts of the standard vitamins and minerals.

Like many other prenatal vitamins, Rainbow Light Prenatal One includes a blend of food powder isolates from raspberry, ginger, and spirulina, to make up for any deficits in fruit and vegetable intake.

On quality testing, it comes in middle of the road:  Seven different ingredients differed from their label-stated amounts by over ten percent, but the worst of these was only 37% off its label claimed amount.

8.  Zahler Prenatal Vitamin + DHA

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Zahler’s prenatal vitamin formulation is a serious supplement that delivers a concentrated dose of many of the critical vitamins and minerals for pregnant women.

Virtually all of the minerals are supplied as amino acid chelates or easily absorbed salts, so the bioavailability of the ingredients in this product should be very good.

One unusual aspect of the formulation is the decision to include the omega 3 fatty acid DHA in an amount of 250 mg.  It’s known that omega 3 fatty acids may help improve maternal mental health during pregnancy (2), but omega 3 fatty acids are usually delivered in higher doses than the 250 mg of DHA present in Zahler Prenatal Vitamin + DHA.

9.  Deva Vegan Prenatal Multivitamin

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If you are a vegetarian or a vegan, it can be especially hard to make sure you are getting the right amount of the essentials for having a healthy baby.

Deva Vegan also includes a number of herbal extracts.  Among these are cinnamon, apple pectin, alfalfa leaf, chamomile, rose hips, and acerola extract.

Usually you can assume herbal extracts at least do no harm, but in the case of prenatal vitamins, you should be extra vigilant—many herbal extracts are poorly understood and not well-studied, so their effects on your baby’s health are unknown.

10.  One a Day Women’s Prenatal Vitamin with DHA

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While the raw nutritional daily values are solid, One a Day Women’s Prenatal Vitamin with DHA leaves a lot to be desired.

The daily values for its ingredients are all at 100%, giving the impression that the supplement’s designers simply wanted to check off all the boxes without putting much thought into the specific formulation.

The sources of the vitamins and minerals tend to be cheap compounds with poor bioavailability—metal oxides that can exacerbate an upset stomach, for example, instead of the more bioavailable and easily digestible amino acid chelates or soluble salts found in better-quality supplements.

Category winners

Best prenatal vitamin overall: Ritual Essential Prenatal

Ritual Essence Prenatal delivers all the essential vitamins and minerals your baby needs, and puts particular care into ensuring the source materials are ultra-pure and free of contaminants. That’s exactly what you want in a prenatal vitamin, which earns it the top overall spot. 

Best prenatal vitamin for breastfeeding: Ritual Essential Prenatal

The importance of prenatal vitamins doesn’t stop at birth. Your baby gets nutrients through breastfeeding, so maintaining a high level of essential vitamins during that period is critical. Ritual Essential Prenatal, with its ample supply of B complex vitamins including folate, is perfectly suited. 

Best prenatal vitamin for women over 35: New Chapter Perfect Prenatal Vitamins

Getting the right vitamins and minerals is even more critical for older women looking to have kids, since nutrients like folate are critical for preventing birth defects.  New Chapter gets it right, providing high doses of all the essentials. 

Best natural prenatal vitamin: Garden of Life Vitamin Code Raw Prenatal 

If you want all of the ingredients in your prenatal vitamin to be naturally-sourced, look no further than Garden of Life. It uses yeast cultures and fruit and vegetable extracts to provide all of the essential vitamins and minerals you need from a prenatal vitamin. 

Best prenatal vitamin prior to conception: Ritual Essential Prenatal

It shouldn’t come as a surprise that the best prenatal vitamin overall is also the best prenatal vitamin to take prior to conception. You need high levels of all the right vitamins and minerals for your entire pregnancy, and Ritual Essentials is the best way to do it. 

Best vegan prenatal vitamin: Garden of Life Mykind Organics Prenatal

Vegans need to pay special attention to their intake of B-complex vitamins and iron. Fortunately, Garden of Life uses whole food, vegan-friendly ingredients to make an excellent prenatal vitamin featuring both of these essential nutrients.

Who should buy prenatal vitamins?

Since a prenatal vitamin is specifically formulated for women who are pregnant, it seems pretty obvious who the target market is for this supplement. However, there are a few subtleties worth considering.

The first is that, if you are actively trying to get pregnant, you should already be taking a prenatal vitamin. The reasoning behind this is that it’s not immediately obvious when you actually conceive a baby, and as a result, you want to make sure your vitamin and mineral levels are optimal for your entire pregnancy.

Furthermore, you should keep taking a prenatal vitamin after giving birth, since your baby is going to get its nutrients via your breast milk as long for as you are breastfeeding.

As you might imagine, optimal levels of vitamins and minerals in your body translate directly to optimal levels of vitamins and minerals into your breast milk. So, prenatal vitamins are not just for women who are currently pregnant.

They are for women who are trying to get pregnant, and for women who have given birth and are still breastfeeding. After you transition away from breastfeeding your baby, you can revert to a standard multivitamin for women, but until then, stick with a prenatal vitamin.

How we ranked

A proper prenatal vitamin requires several key ingredients. According to the Mayo Clinic, prenatal vitamins should absolutely contain folic acid and iron, as these are essential for proper fetal development (1).

So, to even make it into consideration, all potential candidate supplements that we evaluated had to contain both of these essential ingredients.

Having established the bare minimum, we then looked to see which prenatal vitamin products contained other important nutrients for things like brain development and proper hormonal and musculoskeletal function. This included nutrients like omega 3 fatty acids, vitamin D, and calcium.

While these are not quite at the same level of critical importance as folate and iron (which help prevent birth defects), they are nevertheless important to look for if you don’t already take a separate fish oil supplement, vegan omega 3 supplement, and/or a vitamin D supplement.

Prenatal supplements which contained these nutrients garnered a lot of points in our scorings, while those which did not contain any of these important nutrients were dropped. We also looked for trace minerals like copper, zinc, and iodine, and checked the vitamin C and vitamin A levels as well.

Vitamin A in particular is helpful in small amounts, but can be toxic in large amounts, so we immediately ditched anything that had too much vitamin A—it’d be better to take nothing than to take too much vitamin A.

Having established the nutrient content, we then looked at the overall supplement design. More than ever, we prioritized supplement purity above all: when you are pregnant or breastfeeding, you definitely don’t want any extraneous ingredients, artificial colors, or artificial flavorings.

Prenatal vitamins that didn’t meet this high standard also got eliminated from consideration for our rankings.

We sorted the final crop of prenatal vitamins by the dose and potency of their most important vitamin and mineral ingredients, as well as by purity. We’re confident that these are the absolute best prenatal vitamins on the market right now.

Benefits

Prenatal vitamins are formulated based on scientific research on infant health. Prenatal vitamins are special supplements designed with the intent of helping your soon-to-be-born baby to be as healthy as possible.

The focus with prenatal vitamins is to provide nutrients that have been scientifically connected with better fetal development.

In an ideal world, your prenatal supplement is only one facet of ensuring your baby is as healthy as possible—staying healthy during pregnancy in other ways, like getting exercise and eating a well-balanced diet, is part of the equation too.

Given the name, you might think you should start taking prenatal vitamins once you know you are pregnant.  However, this is a mistake! Many critical developmental steps that rely on proper nutrition happen very early on during pregnancy—in the first few weeks.

Once you start considering having a baby, you should already start taking a prenatal vitamin.  The good news is that there is no real downside to taking a quality prenatal vitamin—they provide pretty much the same benefits as a regular womens multivitamin if you don’t get pregnant.

Nutrition during pregnancy determines the health of your baby. As the science of nutrition took off during the 20th century, scientists began to realize how important proper nutrition is during pregnancy.

As a baby develops, it is very vulnerable to nutritional deficiencies, and a deficit of a few critical vitamins and minerals are known to cause problems.

Folate is one of the most important nutrients for fetal development. There is a substantial body of science that connects low levels of vitamin B9 (folate) and vitamin B12 (cobalamin) with an increased risk of neural tube defects, a birth defect that affects the spinal cord as it develops.  Neural tube defects often have very serious medical consequences for the baby.

According to a scientific article published in 1993 by P.N. Kierke and other researchers at the Health Research Board in Dublin, Ireland, blood levels of both folate and vitamin B12 are directly and independently linked to prevention of neural tube defects in infants (2).

The authors followed over 56,000 pregnant women throughout their pregnancy and after childbirth, tracking blood levels of folate and vitamin B12.

The authors then used statistical methods to search for an association between the blood levels of these two vitamins and the probability that the woman’s child would end up with a neural tube defect.  Indeed, the vitamin levels in the blood were strongly correlated with a reduced risk of this type of birth defect.

Moreover, many of the women whose folate and B12 intakes were up to normal dietary standards still had low levels of folate and B12 in their blood, which caused Kierke and co-authors to call for revisions to dietary intake standards.

This research, and other papers like it, spurred the United States Food and Drug Administration to create new standards for fortifying processed foods with folic acid (another form of folate) and vitamin B12 in order to prevent neural tube defects.

As a result, the average blood folate levels in pregnant women more than doubled, but some women still have low levels of folate (3).

Iron is another critical nutrient, especially in the second and third trimester. During pregnancy, your iron needs are also quite high, since you are producing blood for two people instead of one.  According to a 2000 article by Thomas H. Bothwell published in the American Journal of Clinical Nutrition, the total added iron needs during pregnancy sum to over 1000 mg (4).

Much of this required iron comes during the second and third trimester, and many women do not have enough bodily iron reserves to support this demand for iron.

Bothwell writes that, for many women, especially those with a subpar diet, fortification of their food or supplementation of their diet with an iron supplement.  For this reason, almost all prenatal vitamins include iron as a part of their formulation.

The format of the iron supplied varies from product to product—though many different types of iron are absorbable, amino acid chelates tend to be better-tolerated.

Another important consideration is that calcium inhibits iron absorption.  This phenomenon is well-described in a brief by Leif Hallberg published in the American Journal of Clinical Nutrition in 1998 (5).

The interaction is strong enough that most high-quality prenatal vitamins have barely any calcium in them at all.  You should check your prenatal vitamin’s label to make sure there isn’t too much calcium in it.

However, it’s also important to get calcium during pregnancy too. The best strategy to avoid problems is to take a calcium supplement or eat calcium-rich food at least a few hours apart from taking your prenatal vitamin.

A prenatal vitamin with omega 3 fatty acids can help promote brain development in your baby. There is a wide base of scientific evidence indicating that omega 3 fatty acids, such as those found in fish oil or vegan omega 3 supplements, are associated with brain health, but emerging evidence is indicating that it’s at least as important for brain development during pregnancy.

For example, one review study by doctors at Harvard Medical School took stock of the evidence on neurodevelopment and omega 3 fatty acids during pregnancy (6).

They point to evidence indicating that omega-3 fatty acids, and in particular the molecule docosahexaenoic acid (DHA), plays a critical structural role in the brain and the eyes during fetal development.

Further, the authors suggest that women have a higher need for omega-3 fatty acids during pregnancy compared women who are not pregnant.

While people who are not pregnant can get much or all of their omega 3 fatty acid intake from fish sources like salmon if desired, women who are pregnant need to be conscious of the content of mercury in fish: more than two servings per week of fish could expose your baby to unsafe levels of mercury, which has a decidedly negative effect on brain development.

As such, supplementation is really the only game in town when it comes to safely getting enough omega 3 fatty acids in your diet when you are pregnant.

You can achieve this either by taking a fish oil, krill oil, or vegan omega 3 supplement on the side, or making sure you get a prenatal vitamin that includes DHA and EPA, the two most important biologically active omega 3 fatty acids. A number of our top-ranked prenatal vitamins have omega-3s for exactly this reason.

Prenatal vitamins with omega 3 fatty acids might help prevent peripartum and postpartum depression as well. Omega 3 fatty acids have been researched quite a bit in their own right for treating and preventing depression (often performing as well as prescription antidepressants), but it wasn’t until 2008 that randomized clinical trials directly examined omega-3s for the prevention and treatment of depression in pregnant women (7).

Pregnancy itself increases the risk of psychological distress and mental health problems, so if a prenatal vitamin that delivers omega-3s could reduce this risk, that would be an even better reason to take them.

In the experiment, conducted by researchers in China, 62% of the women taking the omega-3 containing supplement responded to treatment, compared to only 27% of the group taking the placebo supplement. These results, though from a small study, make taking a prenatal vitamin that provides omega-3 fatty acids sound like an even better idea.

Side effects

Since they are specifically designed with safety in mind, a quality prenatal supplement should not have any major side effects.  Some women find that consuming high levels of iron (especially in inorganic forms) can cause mild gastrointestinal problems (8).

Still, it’s important to keep your body’s iron stores high during pregnancy, so if this occurs, you can try switching to a prenatal vitamin that supplies iron in a chelated form, or spreading the dosage out throughout the day.

Recommended dosage

Fortunately, the recommended dosage is taken care of by the supplement designers in a quality prenatal vitamin.  You should examine the nutrition facts label to check the levels of four key ingredients, though: vitamin B9 (folate/folic acid), vitamin B12, iron, and calcium.

The Mayo Clinic recommends that you consume at least 400 micrograms (mcg) of folate per day before and during pregnancy, and vitamin B12 and iron should be supplied in amounts close to or exceeding 100% of your daily needs (9).

The calcium content, as mentioned before, should be limited, otherwise you’ll be interfering with your iron absorption.

FAQ

Q: Do prenatal vitamins increase the chance of pregnancy?

A: No, contrary to what the name might suggest, a prenatal vitamin is not actually designed to increase your chance of getting pregnant. Instead, they are designed to make sure your body has the optimal balance of vitamins and minerals to sustain a healthy baby throughout an entire pregnancy.

Some people do resort to fertility supplements in an effort to increase the probability that they’ll get pregnant, as these supplements do include ingredients that (hopefully) make pregnancy more likely.

Regardless, it’s important to recognize that fertility supplements and prenatal vitamins are fundamentally different products with different goals in mind.

Q: When should you take a prenatal vitamin?

A: Experts recommend that you start taking a prenatal vitamin as soon as you begin trying to get pregnant. That’s because of the lag time between when you conceive and when you typically find out that you’re actually pregnant.

Of course, that’s not always possible, so if you do find out that you are pregnant and aren’t taking a prenatal vitamin yet, starting sooner rather than later is a good idea.

Many important fetal milestones in development happen in the first two trimesters, so making sure you have the necessary vitamins and minerals to support this development is very important.

Q: Is it okay to take a prenatal vitamin if you are not pregnant?

A: Yes, the only real difference between a prenatal vitamin and a normal multivitamin for women is that a prenatal vitamin has somewhat higher levels of a few critical ingredients like folate, iron, and vitamin D, to name just a few.

While taking too much iron for a long time (i.e. several months or years) could be undesirable, over the short term, there’s nothing wrong with taking a prenatal vitamin if you are not pregnant. In fact, it’s exactly what many doctors recommend if you think you might become pregnant in the near future.

Q: When should you start taking a prenatal vitamin?

A: Most doctors and experts believe that you should start taking a prenatal vitamin before you get pregnant. Epidemiologists at the Centers for Disease Control and Prevention go as far as recommending that all women of reproductive age, even those who are not planning on getting pregnant, take an adequate amount of folic acid, just because of the drastic benefits in the off-hand chance you do get pregnant.

Of course, this doesn’t mean you need to be taking a prenatal vitamin necessarily, but it won’t hurt. If you think you might get pregnant soon, or are trying to get pregnant, you should already be taking a prenatal vitamin.

And if you are pregnant and haven’t been taking one, you should start today: better late than never. Fetal development is a long process, and proper vitamin levels are important for all of it.

Q: Is it good to take a prenatal vitamin before you get pregnant?

A: Yes, in fact that is precisely what experts at institutions such as the Mayo Clinic recommend (10).

Because of the lag between getting pregnant and finding out that you are pregnant, it’s better to already have the proper levels of vitamins and minerals in your body to support a pregnancy when you conceive, versus waiting several weeks before you find out you’re pregnant to start taking a prenatal vitamin.

Incidentally, it’s also a good idea to keep taking a prenatal vitamin after you give birth, for at long as you are breastfeeding, so that your newborn baby gets the same nutrients via breastmilk.

Q: What should you look for in a prenatal vitamin?

A: The two most important ingredients to look for are folate and iron. These ingredients support proper fetal development and prevent birth defects. Next up, you should also look for vitamin D, omega 3 fatty acids, and calcium.

While the evidence for these ingredients isn’t as strong, there’s still a compelling case to be made that they support proper fetal development and growth. Plus, in the case of omega 3 fatty acids, they will also support your own mental wellbeing during pregnancy.

As you might guess, we used exactly these criteria to evaluate the top prenatal vitamins on the market in our rankings.

Q: How much folic acid should be in a prenatal vitamin?

A: According to the Centers for Disease Control and Prevention, women of reproductive age should look for 400 mg of folic acid in a prenatal vitamin (11).

There is strong scientific evidence that indicates that folic acid supplementation can prevent birth defects like spina bifida and problems with brain development. Any high-quality prenatal vitamin should provide at least this much folic acid per day.

Q: What happens if you miss a prenatal vitamin?

A: If you miss just one dose, it’s not a big deal. Maintaining high levels of vitamins like folic acid and minerals like iron, as well as other nutrients like omega-3 fatty acids, is more about consistent intake versus taking a supplement exactly every 24 hours.

The one potential exception to this is folic acid; it’s both absorbed and excreted relatively rapidly by your body, so if you forget to take a prenatal vitamin in the morning, it’s good to take it when you remember in the afternoon, then return to your usual routine the next day.

That aside, missing a dose here or there is not a huge deal—keep in mind that the clinical research that demonstrated the efficacy of folate supplementation was done on women in the real world, so many of them no doubt forgot to take a dose here and there.

Even in the face of occasional forgetfulness, the results still resoundingly support the benefits of the folate for pregnant women.

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Recap

A prenatal vitamin supplement can be a great way to ensure that you are on the right track for ensuring your baby develops in a healthy way.  Making sure you get enough folate, vitamin B12, and iron are key aspects of a prenatal vitamin.

Remember, if at all possible, you should start taking a prenatal vitamin before you try to get pregnant, as the first few weeks of pregnancy involve some critical development of your baby’s nervous system and spinal cord.

Especially when it comes to choosing a prenatal vitamin, talking to your doctor is a good idea, as you might have some specific individual needs that need to be taken into account when deciding on a prenatal vitamin supplement.

For BodyNutrition’s #1 prenatal recommendation, click here.

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John Davis

John Davis is a Minneapolis-based health and fitness writer with over 7 years of experience researching the science of high performance athletics, long-term health, nutrition, and wellness. As a trained scientist, he digs deep into the medical, nutritional, and epidemiological literature to uncover the keys to healthy living through better nutrition.